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Center for Therapeutic Research and Development Strategy for New Coronavirus Infections (COVID-19)

We are looking for volunteers to take part in a clinical trial.

Our organization has found that a combination of the above can result in a treatment that can be addressed at the household level.

A combined formula of more than along with the oxygen cylinders is effective.
For countries with poor health insurance systems or people without health insurance, this program provides useful information as an emergency measure to prevent people from going to the hospital and surviving.
Basically, both the DNA (RNA) vaccine and a small molecule compound called Avermectin Ivermectin have the ability to induce primary immunity.

The cross-sharing link code is under htmlcode, Spread aroud the world on the earth!

寄付のお振込先は、こちらPlease click here to make your donation to our bank account. https://00m.in/4pCfH
Пожалуйста, нажмите здесь, чтобы сделать пожертвование на наш банковский счет.
Haga clic aquí para hacer su donación a nuestra cuenta bancaria.
https://streamlabs.com/禿太郎/
https://00m.in/4pCfH

Although ACE2 expression levels vary by organ in vivo, ACE2 (Angiotensin-converting enzyme 2, angiotensin-converting enzyme II), also called ACEH, is a zinc metalloproteinase of the ACE family and an important regulator of the renin-angiotensin system.ACE2 has a more restricted tissue distribution than ACE and is found primarily in the heart, kidney, and testis. ACE2 has been shown to be a functional receptor for human coronaviruses, whereas it is detected at low levels in various other tissues. However, it is also known as the causative virus of the common cold (common cold) and we believe that there are quite a few serotypes. Moreover, there must be countless other functional receptors for human coronaviruses besides ACE2. In other words, the myriad of serotypes that exist make it very difficult and impossible to develop an effective vaccine.
Rather, I thought it was necessary to develop multiple drugs to suppress the spread of the virus.
One of the candidates is an RNA polymerase inhibitor that acts specifically on SARS-CoV-2, the virus responsible for the new type of coronavirus infection (COVID-19).
We identified nafamostat (nafamostat mesylate, trade name fusan) as a drug that may efficiently block the viral entry process by preventing the fusion of the viral outer membrane, the first stage of infection of SARS-CoV-2, the virus responsible for the new coronavirus infection (COVID-19), with the cell membrane of the infecting cell. In early March this year, a German group announced the efficacy of a similar drug to nafamostat, camostat mesylate (trade name foipan), against SARS-CoV-2 (Reference 1), but compared to camostat, nafamostat blocked the viral entry process at concentrations less than one-tenth lower.
Both nafamostat and camostat were developed in Japan for the treatment of acute pancreatitis and have already been prescribed in Japan for many years. Adequate clinical data on safety has been accumulated and clinical trials can be conducted promptly.

Camostat(Foipan)https://wikipedia.org/wiki/%E3%83%8A%E3%83%95%E3%82%A1%E3%83%A2%E3%82%B9%E3%82%BF%E3%83%83%E3%83%88
Nafamostat(Futhan)https://wikipedia.org/wiki/%E3%83%8A%E3%83%95%E3%82%A1%E3%83%A2%E3%82%B9%E3%82%BF%E3%83%83%E3%83%88

The RNA polymerase inhibitor that acts specifically on the virus of SARS-CoV-2, the virus that causes the new type of coronavirus infection (COVID-19), We have being investigated, pursued as some candidates.

Honorarium: $3,520 (about £3520) + transportation and accommodation: $700 (about £500). If you are interested in taking a tour of the facility, please fill out the form below to participate in the tour.

https://www.secure-cloud.jp/sf/1589615222VkpRgEWS

About the prescription is a special cold medicine.Our efforts to develop our active ingredients

https://www.thailandmedical.news/

Impotin (KPNA is the molecular symbol) is essential for the transfer of STAT1, which is activated by viral infection, into the nucleus, but ORF6 in SARS virus competitively binds to the impotin and inhibits it, causing the virus to multiply without natural immunity such as interferon. In the presence of ivermectin, this ORF6 (perhaps the same in a new coronavirus?) In this scenario, the binding of STAT1 to its impotin is inhibited, resulting in the restoration of STAT1 function and the restoration of innate immunity to the virus.

https://aasj.jp/news/watch/12749https://aasj.jp/news/watch/12749

Isopropylantipyrine, Acetaminophen, Allylisopropylacetylurea, Anhydrous CaffeineDomperidon 10mg
・Domperidone(Chemical effect class name Digestive tube movement improvement agent)ATC codeA03FA03,KEGG DRUGD01745
・Aldioxa(Gastritis and peptic ulcer treatment)ATCcodeA03FA03

COLD RELIEF Medicine



nauseous stop drugs

Avermectin Ivermectin



Gastritis and peptic ulcer treatment

Domperidone



Cough medicines

cold medicine

Our organization has found that a combination of the above can result in a treatment that can be addressed at the household level.

A combined formula of more than along with the oxygen cylinders is effective.
For countries with poor health insurance systems or people without health insurance, this program provides useful information as an emergency measure to prevent people from going to the hospital and surviving.
Basically, both the DNA (RNA) vaccine and a small molecule compound called Avermectin Ivermectin have the ability to induce primary immunity.

The cross-sharing link code is under htmlcode, Spread aroud the world on the earth!

寄付のお振込先は、こちらPlease click here to make your donation to our bank account. https://00m.in/4pCfH
Пожалуйста, нажмите здесь, чтобы сделать пожертвование на наш банковский счет.
Haga clic aquí para hacer su donación a nuestra cuenta bancaria.
https://streamlabs.com/禿太郎/
https://00m.in/4pCfH
インプレッション型アフィリエイト

An infectious disease is established when the amount of invading bacteria or the virulence exceeds the body’s defense mechanism. As a cause of weakening the resistance to infection, a disease occurs in which bacterial inflammation caused by a novel coronavirus infection spreads to surrounding tissues in various parts. If the inflammation reaches the brain, it may die immediately. The virus may have such pathological properties. I think that the main cause is that different causes of death and symptoms differ depending on humans, and there are definitely multiple mutants in the body. I am currently taking acetylsalicylic acid and ibuprofen together. The symptoms alleviated about 1 hour after oral administration, but I feel that the effect lasted for several hours yesterday. I had this symptom three days ago, so it has continued for quite a long time.

Pay Attention, Please! Be careful, sir.Please be careful.

The following text is a reminder of the basic policy and fees for the application to the human body.
Stromectol (ingredient: ivermectin) Tablets 3mg Dosage and Administration
Intestinal fecal nematodes: Ivermectin is administered orally at a dose of approximately 200 μg per 1 kg of body weight twice at 2-week intervals. The doses per patient weight are shown in the following table. Take this product with water.

  1. scabies: 200 μg of ivermectin per 1 kg of body weight should be administered orally as a single dose. The doses per patient weight are shown in the following table. Take this product with water.
    Dosage per patient weight: 15-24 kg body weight; 3 mg, 25-35 kg body weight; 6 mg, 36-50 kg body weight; 9 mg, 51-65 kg body weight; 12 mg, 66-79 kg body weight; 15 mg, 80 kg or more body weight; approximately 200 μg/kg.
    <Precautions for Use Related to Dosage and Administration
  2. Take this product with water only. Since this drug is a fat-soluble substance and a high-fat diet may increase blood drug levels, it is preferable to administer this drug on an empty stomach.
    There may be a transient exacerbation of pruritus in the early stages of treatment with this drug. Itching may persist as an allergic reaction even after the death of the mite. Do not readminister the drug uncontrollably if no characteristic rash or infection is observed, or if pruritus persists but no characteristic rash or infection is observed.
    In severe cases of keratotic scabies, a second dose should be considered within 1 to 2 weeks after the first dose of this product, including speculation.
    Stromectol Tablets 3mg Indication
  3. intestinal fecal nematosis.
  4. scabies.
    <Precautions for Use Related to Indications
    For scabies, use in patients with a definite diagnosis or who have had contact with the patient and who present symptoms of scabies.

Side Effects of Stromectol Tablets 3mg
Clinical study (clinical trial): In a clinical trial conducted in Japan for intestinal fecal nematodes, 1 out of 50 patients (2.0%) had 2 adverse reactions, 1 case each of nausea and vomiting. In 4 of 50 patients (8.0%), there were a total of 7 laboratory abnormalities: elevated AST (GOT), elevated ALT (GPT), elevated total bilirubin, decreased white blood cell count, increased lymphocyte count, decreased monocyte count, and hematuria in 1 case each.

(Reference) In a clinical study of intestinal fecal nematodes conducted in a foreign country, 20 adverse reactions were observed in 12 (11.0%) of 109 cases. The main adverse reactions were dizziness and pruritus in 3 cases each, and diarrhea and nausea in 2 cases each.

Outcome study (intestinal fecal nematodes): Of 309 patients evaluated for safety, 19 (6.1%) had adverse reactions, the most common being an increase in AST (GOT), 4 each in eosinophil count, and 3 in ALT (GPT) [at the end of the review].

Results of use survey (scabies): Of 750 patients evaluated for safety, adverse reactions were observed in 12 (1.6%), with 3 major cases of hepatic dysfunction [at the end of the survey].

  1. serious side effects
    (1) Toxic Epidermal Necrolysis (TEN) and Stevens-Johnson’s syndrome (Stevens-Johnson’s syndrome) (frequency unknown): Toxic Epidermal Necrolysis (TEN) and Stevens-Johnson’s syndrome may occur.
    (2) Hepatic dysfunction and jaundice (frequency unknown): Hepatic dysfunction and jaundice accompanied by a marked increase in AST (marked increase in GOT) and ALT (marked increase in GPT) may appear.
    (3) Thrombocytopenia (frequency unknown): Thrombocytopenia may be observed closely, and if abnormalities are observed, administration should be discontinued and appropriate measures should be taken.
    Other side effects: If any of the following symptoms or abnormalities occur, take appropriate measures such as discontinuing administration.
    (1) Hypersensitivity: (unknown frequency) Transient exacerbation of itching in patients with scabies, urticaria, (less than 0.1-5%) itching, rash.
    (2) Liver: (unknown frequency) Al-P elevation, (less than 0.1-5%) hepatic dysfunction (AST elevation (GOT elevation), ALT elevation (GPT elevation), total bilirubin elevation, γ-GTP elevation).
    (3) Kidney: (less than 0.1-5%) Elevated BUN.
    (4) Digestive system: (unknown frequency) diarrhea, anorexia, constipation, abdominal pain, (less than 0.1%) nausea, vomiting.
    (5) Psychiatric nervous system: (unknown frequency) Dizziness, somnolence, tremor.
    (6) Blood: (less than 0.1-5%) anemia, increased eosinophil count, (less than 0.1%) decreased white blood cell count, increased lymphocyte count, decreased monocyte count.
    (7) Others: (unknown frequency) asthenia/fatigue, hypotension, bronchial asthma exacerbation, (less than 0.1-5%) elevated LDH, (less than 0.1%) hematuria.
    Precautions for use of Stromectol Tablets 3mg
    [Contraindicated]
    Patients who have a history of hypersensitivity to the ingredients of this product.

Cautious administration.
Patients severely infected by Loa filamentosa [Severe or fatal encephalopathy may occur in rare cases after or independently of administration of antimicrofilarias and, although a causal relationship has not been established with this drug, it may occur].

[Important Basic Note].
If a hypersensitivity reaction to this product is observed, the subsequent administration should be discontinued.
Consider re-administration if fecal larvae do not turn negative.
In the case of easily infected patients (including HIV-infected and HTLV-1-infected patients, etc.), more than the usual number of doses may be required, and even in such cases, cure may not be achieved.

  1. In patients with onchocerciasis or loa filariasis, serious side effects and Mazzotti reactions of the central nervous system (e.g., encephalopathy, headache, coma, altered mental status, difficulty standing, difficulty walking, confusion, lethargy, convulsions, stupor, etc.), musculoskeletal system (e.g., arthralgia), and others (e.g., fever, conjunctival hemorrhage, eye congestion, urinary incontinence, fecal incontinence, edema, dyspnea, back pain, neck pain, etc.) have been reported, so caution should be exercised when administering this drug to patients with these diseases (these reactions may be due to allergic and inflammatory reactions to dead microfilaria).
  2. do not use this product for the treatment of scabies onychomycosis because it is not effective in treating scabies onychomycosis.
    Administration to the elderly
    Safety for the elderly has not been established. In general, elderly people with impaired hepatic, renal, or cardiac function, complications, or concomitant use of other drugs should be administered with caution.

Administration to pregnant women, pregnant women, lactating women, etc.

  1. administer to pregnant women or women who may be pregnant only when the therapeutic benefits outweigh the risks [the safety of administration during pregnancy has not been established, and teratogenicity has been observed in animal studies]. (Reference) Repeated doses of ivermectin at 0.2, 8.1, and 4.5 times the highest recommended human dose in mice, rats, and rabbits, respectively (converted to mg/m2/day), resulted in cleft palates. Forelimb flexion was also noted in the rabbits. These developmental effects only occurred at or near the dose at which maternal toxicity to pregnant animals appeared.
    Lactation should be discontinued during the administration of this product [it has been reported that it has been transferred to human breast milk].
    Administration to children, etc.
    Safety in children weighing less than 15 kg has not been established [limited experience with use].

[Overdose]
In the case of overdose, the following adverse reactions have been reported in humans in accidental poisoning due to oral ingestion, inhalation, injection, or exposure to the body surface of ivermectin for veterinary use (dose unknown): rash, contact dermatitis, edema, headache, dizziness, asthenia, nausea, vomiting, diarrhea, seizures, ataxia, dyspnea, abdominal pain, abnormal sensation, and urticaria.
Treatment: In case of overdose, supportive care with fluid and electrolyte infusion, respiratory maintenance (including oxygen inhalation and artificial respiration), and hypotensive drugs (in case of clinically significant hypotension) should be considered. At the time of overdose, if it is necessary to prevent the absorption of the ingested product, it is advisable to emit as quickly as possible, laxatives and other normal detoxification procedures after gastric lavage.
Notes on Application]
(It has been reported that if the PTP sheet is swallowed by mistake, the hard, sharp edges of the PTP sheet may pierce the esophageal mucosa, causing perforation and serious complications such as mediastinal sinusitis.